7 Essential Facts About CAS No. 1326-66-5 You Should Know

12 Aug.,2025

 

Introduction to CAS No. 1326-66-5

CAS No. 1326-66-5 refers to an organic compound known as aniline, commonly used in chemical synthesis and industrial applications. Understanding the characteristics, uses, and safety aspects of this compound is crucial for researchers and industry professionals alike. In this article, we will explore seven essential facts about CAS No. 1326-66-5 that are important for anyone working with or studying this compound.

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1. Chemical Properties and Structure

Aniline is an aromatic amine with a molecular formula of C6H7N. It possesses a distinctive structure that includes a phenyl group (C6H5) attached to an amino group (–NH2). This structural composition gives it unique properties, including its solubility in organic solvents and its reactivity in electrophilic aromatic substitution reactions.

Property Details
Molecular Weight 93.13 g/mol
Boiling Point 184 °C
Melting Point –6 °C
Solubility Soluble in water, alcohols, ether

2. Industrial Applications

Aniline plays a pivotal role in the production of various chemicals and materials. It serves as a precursor for dyes, plastics, and pharmaceuticals. Influential figures in the chemical industry, like Dr. Oliver B. Davis, emphasize the importance of aniline in the creation of azo dyes, which are widely used in textiles.

  • Dyes: Over 50% of the annual aniline production is used for dye manufacturing.
  • Pharmaceuticals: Aniline derivatives are used in the synthesis of a variety of drugs.
  • Rubber: It is essential in the production of rubber processing chemicals.

3. Safety and Toxicity

While aniline has valuable applications, safety and toxicity are paramount. It is classified as a harmful substance that can produce adverse effects upon exposure. Experts like Dr. Sarah L. Klein advocate for stringent safety measures when handling the compound to prevent health risks.

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  • Health Hazards: Aniline can cause skin irritation and respiratory issues upon prolonged exposure.
  • Environmental Impact: It is toxic to aquatic life and requires careful disposal methods.

4. Regulatory Status

Regulatory bodies like the EPA and OSHA monitor the usage of aniline, ensuring compliance with safety standards. As noted by industry leaders, such as Ms. Linda T. Jones, it’s essential for companies to stay updated on regulations concerning CAS No. 1326-66-5 to avoid legal repercussions.

Regulatory Body Regulation
EPA Control of hazardous substances
OSHA Occupational Safety Standards
REACH (EU) Registration and Evaluation of Chemicals

5. Methods of Production

There are several methods for synthesizing aniline, primarily using nitrobenzene reduction or through the hydrolysis of phenyl isocyanate. Highly respected chemists emphasize the importance of efficient and safe production methods to minimize environmental impact.

  • Nitrobenzene Reduction: A common laboratory/process industry method.
  • Hydrolysis of Phenyl Isocyanate: Provides a viable alternative production pathway.

6. Aniline in Research

Aniline is frequently used in chemical research due to its reactivity and versatility. Research conducted by universities, such as MIT, often focuses on developing new applications for aniline derivatives in material science and nanotechnology.

  • Nano-materials: New forms of aniline-based compounds are being explored in electronics.
  • Biochemistry: Aniline derivatives are being studied for their potential in drug development.

7. Conclusion

Understanding CAS No. 1326-66-5 is essential for anyone involved in its application or study. From its chemical properties and industrial uses to safety regulations and research potentials, aniline continues to be a compound of significant interest. By recognizing the various aspects of aniline, professionals can leverage its benefits while ensuring safe and responsible use.

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